About

I’m Sophia D’Angelo, a health economist and applied health policy researcher based in North Carolina.

At RTI International, I support research that helps federal, nonprofit, and commercial health stakeholders understand the value, cost, implementation, and impact of healthcare programs and public health interventions. My work includes economic modeling, budget impact analysis, evidence synthesis, mixed-methods research, data analysis, technical writing, and project coordination.

Much of my recent work has focused on HIV prevention economics, including PrEP cost and impact modeling, long-acting injectable prevention options, payer-relevant cost scenarios, and population-level estimates of infections averted and medical cost offsets. I have also supported CMS drug policy and payment-related work through structured evidence reviews, patient values and preferences synthesis, quality reporting support, and analytic deliverables designed to inform policy and operational decisions.

I’m drawn to work that is rigorous, practical, and useful: research that helps decision-makers understand tradeoffs, evaluate evidence, anticipate implementation challenges, and improve access to effective care.

My current professional interests include HEOR, market access, evidence strategy, health economics, public health policy, program evaluation, and healthcare decision support.

I earned my Master of Science in Health Policy and Economics from Cornell University and my Bachelor of Science in Biology from Saint Michael’s College, where I also completed minors in Accounting and Chemistry.

My training in biology, health policy, and economics gives me a practical foundation for working across clinical, economic, and policy questions. I enjoy projects that require both analytical rigor and clear communication: building models, reviewing evidence, interpreting data, and translating technical findings into language that decision-makers can use.

At RTI, I have contributed to projects involving HIV prevention, CMS drug policy implementation, oncology payment models, chronic disease prevention, patient-centered cost research, caregiving access, behavioral health prevention, post-acute care quality, and federal issue briefs.

I bring a structured, reliable, and detail-oriented approach to applied research. I’m comfortable working across multidisciplinary teams, managing competing deadlines, documenting assumptions, communicating clearly with project leads and clients, and turning ambiguous questions into organized analytic plans.

I’m especially effective in roles that require careful evidence review, quantitative reasoning, strong writing, project organization, and practical judgment. I like work that asks not only “What does the evidence say?” but also “What does this mean for decision-making?”

• Health economics

• HEOR and value evidence

• Cost-effectiveness analysis

• Budget impact analysis

• Economic burden analysis

• Scenario and sensitivity analysis

• HIV prevention economics

• PrEP access and impact modeling

• CMS evidence review and policy support

• Patient-centered outcomes research

• Program evaluation

• Mixed-methods research

• Literature reviews and evidence synthesis

• Technical writing

• Stakeholder-facing reports and presentations

• Project coordination and task management

• Stata

• Excel

• R

• TreeAge

• DistillerSR

• EndNote

• Jira

• Qualitative interviews

• Thematic analysis

• Economic modeling

• Literature review

• Survey and claims data analysis

• Technical report writing

• Peer-reviewed manuscript development